I have similar. The trainer is activated, I can not turn on research and culture. Others turn on but do not work. The only thing that works is immortality (a bit strange because the unit "dies" but can still move and attack) and building buildings.
It is posible to use trainer 1.10 Steam on Tropico 5 v1.10 GOG if you rename exe, but it seams that only working options are research and swiss account (maybe coruption).
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