Deus Ex: Human Revolution

[Someonelse]

I was playing last night with the trainer and it worked great. When I shut off my computer it automatically downloaded some updates. Then, this morning, when I turned it on and tried to play again it first wouldn't let me use the trainer at all, it would load but I couldn't click on any options and the functions keys didn't work to activate the options. I also had some mods in the folder, which I deleted. Then the function keys worked. But once they started working again and I loaded the game up, suddenly half the keys on my keyboard won't work. I can use W, S, A & D to move around, but I can't use any weapons. I checked the options, just to make sure the keys are still assigned properly, and they are. I can't figure out how to fix this.
Does anyone have any suggestions please?