Hi, just wanted to report a bug.
Whenever I have activated the F6 and/or F7 options (Inf. Car Nitro and Jumping, respectively) in a session, I am unable to talk to NPCs that give side quests. In my case, I was not able to speak to Hydaria for Cora's personal quest. Even disabling those cheats before talking to the NPC will not work, only a full reset will allow me to speak to the NPC, or else it will not cut to the cutscene after I hold E and gets Ryder stuck standing there with the 'hold E' prompt still up while things in the background were still working.